GAMMACA2 Antibody
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Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
GAMMACA2 antibody; APFI antibody; At1g47260 antibody; F8G22.2 antibody; Gamma carbonic anhydrase 2 antibody; mitochondrial antibody; AtCA2 antibody; GAMMA CA2 antibody; EC 4.2.1.- antibody; Transcription factor APFI antibody
Target Names
GAMMACA2
Uniprot No.
Target Background
Function
GAMMACA2 is an enzyme involved in the catabolism of H(2)CO(3), but it does not mediate the reversible hydration of carbon dioxide. It plays a critical role in mediating complex I assembly in mitochondria and respiration. GAMMACA2 binds to HCO(3)- and is essential for male fertility during anther development and dehiscence. Its function is to regulate the secondary thickenings of the endothecial cell wall, likely through modulating H(2)O(2)-dependent lignin polymerization.
Gene References Into Functions
- At1g47260, the gene encoding GAMMACA2, is essential for complex I assembly and reproductive development, as demonstrated by its requirement for complex I function. PMID: 26889912
- AT1G47260 contributes significantly to maintaining efficient photosynthesis under ambient (photorespiratory) conditions. PMID: 26148112
- At1g47260 is crucial for complex I assembly in plant mitochondria and respiration. PMID: 15935378
- Research suggests that reduction in ROS inhibits H(2)O(2) dependent lignin polymerization in CA2 over-expressing plants, leading to male sterility. PMID: 19326245
- Plant gammaCAs, such as GAMMACA2, do not act as carbonic anhydrases. However, they possess a related activity that likely contributes to CO(2) recycling in the context of photorespiration. PMID: 19808034
Database Links
Protein Families
Gamma-class carbonic anhydrase family
Subcellular Location
Mitochondrion membrane; Peripheral membrane protein; Matrix side.
Tissue Specificity
Constitutively expressed in roots and leaves, with higher levels in flowers, particularly in tapetal tissue of anthers, inflorescence (IM) and floral meristems (FM).
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