At2g04570 Antibody

Gene Overview and Functional Role

AT2G04570 (aliases: GGL14, OSP1) is a member of the GDSL esterase/lipase family, characterized by enzymatic activity in lipid processing and stress responses. Key features include:

Key Findings

• Stomatal Function: OSP1 is preferentially expressed in stomatal guard cells and regulates aperture under light and hormonal cues .

• Expression Patterns: Downregulated in Col-TM (compared to wild-type Col-CK) and Ler-TM (vs. Ler-CK) under stress conditions .

• Protein Interactions: Associates with pathways involving ER stress response and lipid homeostasis .

Research Insights and Potential Antibody Applications

While no studies explicitly describe an antibody targeting OSP1, its role in plant physiology suggests potential applications for functional analysis.

Gene Expression and Stress Response

Proteomic analyses reveal AT2G04570 is differentially expressed during stress, such as:

Antibody Development for Functional Studies

An At2g04570 Antibody could enable:

1. Immunolocalization: Mapping OSP1 distribution in stomatal guard cells.

2. Enzyme Activity Assays: Measuring esterase/lipase activity in lipid metabolism.

3. Protein Interaction Studies: Identifying partners in ER stress or lipid signaling pathways .

Challenges and Future Directions

1. Limited Antibody Availability: No commercial antibodies are reported for OSP1 in the provided literature.

2. Functional Redundancy: Overlapping roles with other GDSL enzymes may complicate target specificity.

3. Stomatal Research: Antibodies could validate OSP1’s role in light-induced stomatal opening .