GDU5 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
GDU5 antibody; At5g24920 antibody; F6A4.130Protein GLUTAMINE DUMPER 5 antibody
Target Names
GDU5
Uniprot No.
Target Background
Function
GDU5 Antibody targets a protein that is likely a subunit of an amino acid transporter. This protein plays a crucial role in regulating amino acid metabolism by stimulating amino acid export through the activation of non-selective amino acid facilitators.
Database Links
Protein Families
GLUTAMINE DUMPER 1 (TC 9.B.60) family
Subcellular Location
Membrane; Single-pass membrane protein.
Tissue Specificity
Expressed in the vascular tissues. Also detected in guard cells.
Q&A
Advanced Research Questions
What experimental strategies resolve contradictory findings in anti-ganglioside antibody pathogenicity studies?
Three evidence synthesis approaches from recent studies:
A. Glycolipid complex profiling
Combinatorial arrays testing 15 glycolipids + 1 phospholipid complexes identified:
B. Epitope spreading analysis
Longitudinal serum sampling reveals:
C. Functional validation
Adoptive transfer models demonstrate:
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IgG Fc galactosylation status modulates macrophage activation (p<0.001)
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Mannose-glycan recognition required for inflammasome activation (NF-κB/CARD9 pathway)
How can antibody glycosylation patterns improve prognostic models?
Recent advancements integrate:
Implementation challenges:
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Requires standardization of glycoanalytical platforms (CV >15% inter-lab)
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Combines poorly with existing Erasmus GBS Outcome Score (ΔAUC=0.03)
Technical Validation Framework
Experimental Confounders in Anti-Ganglioside Research
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