GH3.1 Antibody
Shipped with Ice Packs 
In Stock 
Description
Applications of GHAntibodies
GH3.1 antibodies are widely used in:
Enzyme Kinetics of GH3 Family Proteins
Data from kinetic assays of GH3 homologs reveal substrate preferences :
| Protein | Substrate | Acyl Substrate | (min⁻¹) | (mM) | (min⁻¹ mM⁻¹) |
|---|---|---|---|---|---|
| PtGH3.6 | Asp | IAA | 571 ± 93 | 0.12 ± 0.05 | 4,680 |
| SbGH3.11 | Glu | 2,4-D | 0.61 ± 0.03 | 0.63 ± 0.06 | 1.0 |
| AtGH3.11 | Asp | JA | 382 ± 35 | 0.13 ± 0.03 | 2,920 |
Note: AtGH3.11 (JAR1) shows high specificity for jasmonate conjugation, critical for stress responses .
Functional Insights
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Pathogen Defense: JAR1 knockout plants exhibit impaired JA-Ile synthesis and increased susceptibility to necrotrophic fungi .
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Morphogenesis: Anti-EGF receptor antibodies (e.g., 2G2-IgM) in GH3 pituitary cells induce prolactin synthesis and cytoskeletal changes, mimicking EGF effects .
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Cancer Research: GHDC overexpression in mammary tumors correlates with STAT3/5 signaling dysregulation .
Challenges and Future Directions
Product Specs
Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
GH3.1 antibody; At2g14960 antibody; T26I20.12Probable indole-3-acetic acid-amido synthetase GH3.1 antibody; EC 6.3.2.- antibody; Auxin-responsive GH3-like protein 1 antibody; AtGH3-1 antibody
Target Names
GH3.1
Uniprot No.
Target Background
Function
This antibody targets GH3.1, an enzyme that catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates. This process represents a key mechanism by which plants regulate and respond to excess auxin.
Database Links
Protein Families
IAA-amido conjugating enzyme family
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