GMFB Antibody

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In Stock

Product Specs

Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid freeze/thaw cycles.
Lead Time
Typically, we can ship your orders within 1-3 business days of receipt. Delivery times may vary depending on the method of purchase and location. For specific delivery timeframes, please consult your local distributors.
Synonyms
Glia maturation factor beta antibody; GMF antibody; GMF-beta antibody; GMFB antibody; GMFB_HUMAN antibody
Target Names
GMFB
Uniprot No.

Target Background

Function
GMFB Antibody is a crucial protein involved in various biological processes. Its functions include promoting differentiation of brain cells, stimulating neural regeneration, and inhibiting proliferation of tumor cells.
Gene References Into Functions
  1. GMF-beta plays a significant role in the progression of glioma by promoting neovascularization. PMID: 26515590
  2. The presence of GMF-immunoreactive cells in and around amyloid plaques and neurofibrillary tangles suggests a potential involvement of GMF in inflammatory responses through reactive glia and a role in Alzheimer disease pathology. PMID: 22035352
  3. GMF co-localizes with amyloid plaques and neurofibrillary tangles in Alzheimer brains, indicating a significant upregulation of GMF expression in conditions of neurodegeneration. PMID: 21835226
  4. A notable increase in GMF beta protein expression levels is observed in IFN beta-1a treated LX-2 cells. PMID: 18171522
  5. GMFB promotes T-cell differentiation into CD4-/CD8+ cells when analyzed by two-color flow cytometry. PMID: 16115230

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Database Links

HGNC: 4373

OMIM: 601713

KEGG: hsa:2764

STRING: 9606.ENSP00000350757

UniGene: Hs.151413

Protein Families
Actin-binding proteins ADF family, GMF subfamily

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