RACK1C Antibody
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Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
RACK1C antibody; At3g18130 antibody; MRC8.11Receptor for activated C kinase 1C antibody; Guanine nucleotide-binding protein subunit beta-like protein C antibody
Target Names
RACK1C
Uniprot No.
Target Background
Function
RACK1C is a minor component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways. It is involved in multiple hormone responses and developmental processes. This MAPK cascade scaffolding protein is implicated in the protease IV and ArgC signaling pathway but not the flg22 pathway.
Gene References Into Functions
- Structural analysis reveals a stable protein core with flexible regions, indicating the complex interplay of its structure and function. PMID: 24591271
- The cbl1 null mutant showed upregulation of Receptor for activated C kinase 1C (RACK1C), a WD40 repeat protein. Two rack1c mutant lines exhibited decreased tolerance to salt stress, suggesting RACK1C's role in salt stress resistance. PMID: 22002954
- RACK1 may be crucial for normal production of 60S and 80S ribosomes, with its activity potentially regulated by abscissic acid (ABA). [RACK1C] PMID: 21098678
- The first crystal structure of a RACK1 protein, RACK1 isoform A from Arabidopsis thaliana, was determined at 2.4 A resolution. PMID: 18715992
- RACK1C (At3g18130) exhibits functional equivalence to RACK1A and is positively regulated by other RACK1 genes. PMID: 18947417
- RACK1 genes act redundantly to negatively regulate ABA responses during seed germination and early seedling development. PMID: 19584117
- An enhanced effect on ABA hypersensitivity was observed between rack1a and gpa1 or agb1 mutants in ABA inhibition of cotyledon greening and root growth. RACK1 and AGB1 may not physically interact with each other. PMID: 19651700
Database Links
Protein Families
WD repeat G protein beta family, Ribosomal protein RACK1 subfamily
Tissue Specificity
Widely expressed.
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