Function
HDAC2 is a histone deacetylase responsible for removing acetyl groups from lysine residues located on the N-terminal tails of core histones (H2A, H2B, H3, and H4). This deacetylation process serves as an epigenetic mark for transcriptional repression, playing a crucial role in regulating gene expression, cell cycle progression, and developmental processes. HDAC2 functions within large multiprotein complexes, contributing to the intricate control of chromatin structure and gene activity.