3BETAHSD/D2 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
3BETAHSD/D2; RTNLB19; At2g26260; T1D16.10; 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; At3BETAHSD/D2; 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase isoform 1-2; Reticulon-like protein B19; AtRTNLB19; Sterol-4-alpha-carboxylate 3-dehydrogenase 2, decarboxylating
Target Names
3BETAHSD/D2
Uniprot No.

Target Background

Function
This antibody targets 3β-hydroxysteroid dehydrogenase/decarboxylase (3βHSD/D), an enzyme involved in sterol biosynthesis. Specifically, it catalyzes the conversion of 3β-hydroxysteroids-4α-carboxylate to 3-oxosteroids. This enzyme plays a role in regulating inflorescence internode and leaf growth, potentially by influencing auxin transporter activity through modulation of membrane sterol composition.
Gene References Into Functions

Studies suggest that Arabidopsis 3βHSD/D genes impact auxin transporter activity, possibly by altering membrane sterol composition. PMID: 22673766

Database Links

KEGG: ath:AT2G26260

STRING: 3702.AT2G26260.1

UniGene: At.38921

Protein Families
3-beta-HSD family
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.

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