SCRM Antibody
Description
Possible Interpretations of "SCRM Antibody"
Given the absence of explicit references, the term could be misinterpreted or conflated with existing antibody types:
Key Limitations in Current Data
The provided sources emphasize well-characterized antibody types and therapeutic applications but lack mention of "SCRM Antibody." Critical gaps include:
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Terminology Discrepancies: No standardized abbreviation or full name matches "SCRM" in immunology.
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Structural/Functional Data: No descriptions of antigen specificity, binding mechanisms, or clinical applications.
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Research Context: No studies cite "SCRM Antibody" in diagnostic/therapeutic trials or basic science.
Recommendations for Further Inquiry
To address the ambiguity, consider the following steps:
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Verify Terminology: Cross-check with original sources or databases (e.g., PubMed, Cochrane) for alternative spellings.
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Explore Contextual Clues: Determine if "SCRM" refers to a specific:
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Disease-Associated Antibody (e.g., autoimmune, cancer).
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Antigen Target (e.g., viral protein, tumor marker).
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Consult Emerging Research: Recent advancements in antibody engineering (e.g., scFv libraries , SARS-CoV-2 neutralizers ) may include novel terms.
Synthesis of Relevant Antibody Research
While "SCRM Antibody" remains undefined, the following data highlights analogous antibody types and their applications:
Table 1: Antibody Types and Applications
Product Specs
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Target Background
- MPK3 and MPK6 can phosphorylate ICE1, a basic-helix-loop-helix transcription factor that regulates the expression of CBF genes. PMID: 29056551
- The unified ICE-CBF pathway provides transcriptional feedback control of freezing tolerance during cold acclimation. PMID: 26311645
- Seedling growth was significantly reduced in a T-DNA insertion mutant of ICE1, ice1-2, when grown on 1/2 MS medium lacking sugars, but was restored to wild-type (WT) levels by supplementation with 56 mM glucose. PMID: 26048037
- The ICE2 gene has originated from a duplication event approximately 17.9MYA, followed by sub- and neofunctionalization of the ancestral ICE1 gene. PMID: 25443829
- Research has uncovered the unexpected roles of OST1 in modulating C-repeat-binding factor-dependent cold signaling in Arabidopsis. PMID: 25669882
- Evidence suggests that the ZHOUPI/ICE1 complex might have ancient origins, acquiring novel megagametophyte-specific functions in heterosporous land plants that were conserved in the angiosperm endosperm. PMID: 24553285
- Jasmonate functions as a critical upstream signal of the ICE-CBF/DREB1 pathway to positively regulate Arabidopsis freezing tolerance. PMID: 23933884
- The serine 403 to alanine substitution enhances the transactivation activity of ICE1 and the freezing tolerance of Arabidopsis. PMID: 21447070
- The inducer of CBF expression1 (ICE1) protein, which is involved in the transcriptional control of cold responses, has been found to bind to a MYC element in the BAP1 promoter and is required for the cooling induction of BAP1. PMID: 21098676
- Regulon genes repressed by siz1 did not affect the expression of ICE1, which encodes a MYC transcription factor. PMID: 17416732
