IL20RB Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid repeated freeze-thaw cycles.
Lead Time
Typically, we can ship your orders within 1-3 business days of receiving them. Delivery times may vary depending on the purchase method and location. For specific delivery timelines, please consult your local distributors.
Synonyms
DIRS1 antibody; Fibronectin type III domain containing 6 antibody; FNDC6 antibody; I20RB_HUMAN antibody; IL 20R beta antibody; IL 20R2 antibody; IL-20 receptor subunit beta antibody; IL-20R-beta antibody; IL-20R2 antibody; IL-20RB antibody; IL20RB antibody; Interleukin 20 receptor beta antibody; Interleukin 20 receptor beta chain precursor antibody; Interleukin 20 receptor II antibody; Interleukin-20 receptor subunit beta antibody; MGC34923 antibody
Target Names
Uniprot No.
Target Background
Function
The IL20RA/IL20RB dimer serves as a receptor for IL19, IL20, and IL24. The IL22RA1/IL20RB dimer acts as a receptor for IL20 and IL24.
Gene References Into Functions
- Trabecular meshwork cells express IL-20 receptors. Mutation of the T104 residue in IL-20R2 results in reduced STAT3 phosphorylation and decreased matrix metalloproteinase activity. PMID: 24455976
- The crystal structure of the IL-20/IL-20R1/IL-20R2 complex reveals the mechanism by which type I and II complexes differentiate between cognate and non-cognate ligands. PMID: 22802649
- Researchers have investigated the hypothesis that genetic variations in the IL-20-RI gene influence susceptibility to psoriasis, and analyzed single nucleotide polymorphisms (SNPs) in the IL20RA and IL20RB genes in psoriasis patients. PMID: 18480827
Database Links
Protein Families
Type II cytokine receptor family
Subcellular Location
Membrane; Single-pass type I membrane protein.
Tissue Specificity
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
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