ILDR2 Antibody
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In Stock 
Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (12-14 weeks)
Synonyms
ILDR2 antibody; C1orf32Immunoglobulin-like domain-containing receptor 2 antibody
Target Names
ILDR2
Uniprot No.
Target Background
Function
ILDR2 may play a role in lipid homeostasis and endoplasmic reticulum (ER) stress pathways.
Gene References Into Functions
- Research has shown that ZNF70 interacts with ZFP64 and activates HES1 transcription by binding to the HES1 promoter. Additionally, HES1 gene expression is elevated in ILDR2-knockdown HepG2 cells, where ZNF70 translocates from the cytoplasm to the nucleus. This suggests that ZNF70's movement to the nucleus, after disassociating from the ILDR2-ZNF70 complex, activates HES1 transcription. These findings support a novel connection between ZNF70 and HES1 transcription, potentially involving ILDR2. PMID: 27353377
- Clinical trial investigating the association between genes and diseases, as well as gene-environment interactions. (HuGE Navigator) PMID: 20379614
- Observational study examining the association between genes and diseases. (HuGE Navigator) PMID: 19536175
- Observational study examining the association between genes and diseases. (HuGE Navigator) PMID: 19064610
Database Links
Protein Families
Immunoglobulin superfamily, LISCH7 family
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
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