ITFG1 Antibody

Shipped with Ice Packs
In Stock

Product Specs

Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid repeated freeze-thaw cycles.
Lead Time
Typically, we can ship the products within 1-3 business days after receiving your order. Delivery times may vary depending on the purchase method and location. Please consult your local distributor for specific delivery times.
Synonyms
ITFG1; LNKN-1; TIP; CDA08; T-cell immunomodulatory protein; Protein TIP; Integrin-alpha FG-GAP repeat-containing protein 1; Linkin
Target Names
ITFG1
Uniprot No.

Target Background

Function
ITFG1 Antibody is a modulator of T-cell function. It has demonstrated a protective effect in graft versus host disease models.
Gene References Into Functions
  1. The interaction between RUVBL1 and ITFG1 is essential for collective invasion and progression of breast cancer cells. PMID: 28341484
  2. Changes in cellular levels of TIP influence the phosphorylation state of a specific protein substrate of ataxia-telangiectasia mutated (ATM)/ATM- and Rad3-related (ATR) kinases. PMID: 17384681
Database Links

HGNC: 30697

OMIM: 611803

KEGG: hsa:81533

STRING: 9606.ENSP00000319918

UniGene: Hs.42217

Protein Families
TIP family
Subcellular Location
Secreted. Membrane; Single-pass type I membrane protein.
Tissue Specificity
Ubiquitously expressed.

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