KCR1 Antibody

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In Stock

Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (made-to-order)
Synonyms
KCR1 antibody; At-YBR159 antibody; GL8 antibody; At1g67730 antibody; F12A21.31 antibody; Very-long-chain 3-oxoacyl-CoA reductase 1 antibody; EC 1.1.1.330 antibody; Beta-ketoacyl reductase 1 antibody; AtKCR1 antibody; Protein GLOSSY 8 antibody; gl8At antibody
Target Names
KCR1
Uniprot No.

Target Background

Function
KCR1 is a beta-ketoacyl-coenzyme A reductase essential for the elongation of fatty acid precursors to sphingolipids, triacylglycerols, cuticular waxes, and suberin. It catalyzes the initial reduction step in very-long-chain fatty acid (VLCFA) biosynthesis. RNA interference (RNAi)-mediated knockdown of KCR1 results in plants exhibiting fused vegetative and reproductive organs, and abnormal trichome, epidermal cell, and root morphology. This phenotype is not complemented by KCR2.
Gene References Into Functions
AtKCR1 is a functional beta-ketoacyl-coenzyme A reductase isoform involved in microsomal fatty acid elongation. [PMID: 19439572](https://www.ncbi.nlm.nih.gov/pubmed/19439572)
Database Links

KEGG: ath:AT1G67730

STRING: 3702.AT1G67730.1

UniGene: At.22586

Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity
Expressed in green siliques, flowers, inflorescence stems, leaves and roots.

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