KIAA0100 Antibody
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In Stock 
Product Specs
Buffer
The antibody is provided as a liquid solution in PBS containing 50% glycerol, 0.5% bovine serum albumin (BSA), and 0.02% sodium azide.
Form
Liquid
Lead Time
Typically, we can ship the products within 1-3 business days after receiving your order. Delivery times may vary depending on the purchase method or location. For specific delivery timelines, please consult your local distributors.
Synonyms
Antigen MLAA-22 antibody; BCOX antibody; BCOX1 antibody; Breast cancer-overexpressed gene 1 protein antibody; CT101 antibody; DKFZp686M0843 antibody; K0100_HUMAN antibody; KIAA0100 antibody; MGC111488 antibody; MGC134981 antibody; UPF0378 protein KIAA0100 antibody
Target Names
KIAA0100
Uniprot No.
Target Background
Function
KIAA0100 antibody may be involved in membrane trafficking processes.
Gene References Into Functions
- Reduced expression of miR-195 and subsequent uncontrolled upregulation of BCOX1 (the gene encoding KIAA0100) may contribute to prostate cancer metastasis. PMID: 26338045
- Elevated BCOX1 expression may serve as a novel marker of poor prognosis and a potential therapeutic target for patients with invasive ductal breast carcinomas. PMID: 24489812
- MLAA-22, also known as BCOX1, is a novel acute monocytic leukemia-associated antigen gene located on chromosome 17q11.2. PMID: 18549609
- BCOX1 mRNA expression is primarily localized within the cytoplasm of breast carcinoma epithelial cells. Its mRNA expression is moderately elevated in ductal in situ carcinoma, reaching a peak in invasive breast carcinoma and metastatic breast carcinoma cells (MET). PMID: 16289875
Protein Families
SABRE family
Subcellular Location
Secreted.
Tissue Specificity
Expressed in pancreas, placenta and up-regulated in breast carcinoma epithelial cells, ductal in situ carcinoma (DCIS), invasive breast carcinoma (IBC) and metastatic breast carcinoma cells (MET).
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