TK1B plays a crucial role in the salvage pathway for purine and pyrimidine deoxyribonucleotide synthesis. It demonstrates preferential phosphorylation of purines over pyrimidines.
Gene References Into Functions
Research has elucidated the specialized function of two thymidine kinases (TKs) in Arabidopsis thaliana. This study establishes that the nucleotide salvage pathway mediated by these kinases is essential for plant growth and development. [AtTK2] PMID: 26139575