KTI12 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
KTI12 antibody; DRL1 antibody; ELO4 antibody; At1g13870 antibody; F16A14.8Protein KTI12 homolog antibody; AtKTI12 antibody; At1g13870 antibody; Protein DEFORMED ROOTS AND LEAVES 1 antibody; AtDRL1 antibody; Protein ELONGATA4 antibody
Target Names
KTI12
Uniprot No.
Target Background
Function
DRL1 is an Elongator-associated factor that transiently interacts with the Elongator complex, facilitating its association with elongation-competent RNA polymerase II. It plays a significant role in regulating both meristem activity and organ growth, acting as a positive regulator of adaxial leaf patterning by modulating cell division and differentiation. DRL1 is essential for an early step in the synthesis of 5-carbamoylmethyl (ncm5) groups present on uridines (ncm5U) at the wobble position in tRNA.
Gene References Into Functions
- DRL1, the Elongator complex-associated protein, plays a crucial role in enhancing immune responses against necrotrophic fungal pathogens in Arabidopsis. PMID: 27868335
- Genetic complementation studies have demonstrated the conserved functions of Arabidopsis DRL1 and yeast KTI12. PMID: 25518926
- DRL1 has been implicated in the regulation of brassinosteroids homeostasis. PMID: 23204503
Database Links
Protein Families
KTI12 family
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Expressed in roots, hypocotyls, cotyledons, shoot apices, stems, inflorescence apices, leaves and flowers.
Quick Inquiry
Personal Email Detected
Please use an institutional or corporate email address for inquiries. Personal email accounts ( such as Gmail, Yahoo, and Outlook) are not accepted. *
