nadl1.2 Antibody

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Description

Potential Nomenclature Clarification

The term "nadl1.2" may involve typographical errors or unconventional naming conventions. Key considerations include:

CandidateRationaleRelevance to Search Results
NADK2 AntibodyMatches nomenclature patterns (e.g., NADK2 is a mitochondrial NAD kinase) .Discussed in as Rabbit mAb #82073 targeting NADK2.
NALD1 AntibodyHypothetical expansion (NALD1: N-Acetyl-Linked Domain 1).Not referenced in sources.
NAD-Linked EnzymesBroader category (e.g., dehydrogenases).Indirectly related to .

Analysis of NADK2 Antibody (Closest Identified Match)

While not directly addressing "nadl1.2," the search results provide detailed data on NADK2 Antibody (Cell Signaling Technology #82073):

Research Findings

ParameterData
SensitivityDetects endogenous NADK2 (~45 kDa) .
ValidationConfirmed via CRISPR-Cas9 knockout studies .
Pathological RelevanceLinked to mitochondrial redox balance and cancer cell proliferation .

Recommendations for Clarification

To resolve ambiguity, consider the following steps:

  1. Verify Target Name: Confirm spelling (e.g., NADK2 vs. NADL1.2).

  2. Check Alternate IDs: Use UniProt or NCBI Gene databases for aliases.

  3. Supplier-Specific Queries: Contact antibody vendors (e.g., Cell Signaling, Bio-Techne) for unpublished catalog entries.

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
nadl1.2 antibody; Neural cell adhesion molecule L1.2 antibody; N-CAM-L1.2 antibody; NCAM-L1.2 antibody; Fragment antibody
Target Names
nadl1.2
Uniprot No.

Target Background

Function
Nadl1.2 Antibody is a cell adhesion molecule that plays a crucial role in the development of the nervous system. It is involved in various functions, including neuron-neuron adhesion, neurite fasciculation, and neurite outgrowth. Nadl1.2 Antibody binds to axonin on neurons.
Database Links
Protein Families
Immunoglobulin superfamily, L1/neurofascin/NgCAM family
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cell projection, growth cone.
Tissue Specificity
Expressed in many postmitotic neurons in 16-36 hours embryos. Little or no expression in the olfactory placode, the anterior lateral line/acoustic ganglia complex, the posterior lateral line ganglion, late-developing hindbrain neurons and some Rohon-Beard

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