LA1 Antibody

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Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
LA1 antibody; At4g32720 antibody; F4D11.80La protein 1 antibody; AtLa1 antibody
Target Names
LA1
Uniprot No.

Target Background

Function
This antibody binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Gene References Into Functions
  1. The AtMC4 protein plays a critical role in regulating stem cell homeostasis by catalyzing the cleavage of AtLa1 protein in response to environmental stresses. PMID: 29241568
  2. Inactivation of AtLa1 (At4g32720) function results in lethality and an early developmental arrest of the embryo. PMID: 17459889
Database Links

KEGG: ath:AT4G32720

STRING: 3702.AT4G32720.1

UniGene: At.2236

Subcellular Location
Nucleus, nucleoplasm. Nucleus, nucleolus.
Tissue Specificity
Expressed ubiquitously (at protein level).

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