LBD16 Antibody

LBD16 is a transcriptional activator involved in lateral root formation. Its activity is regulated by the transcriptional activators ARF7 and ARF19. LBD16 functions in both the initiation and emergence of lateral roots, collaborating with LBD18 downstream of ARF7 and ARF19. Its activity is further positioned downstream of the auxin influx carriers AUX1 and LAX1 in the regulatory pathway of lateral root initiation and development.

Key functional aspects of LBD16, supported by the following literature:

1. Conserved Leu or Val residues within the coiled-coil motifs of LBD16 and LBD18 are crucial for their dimerization and subsequent transcriptional regulation, ultimately determining their biological functions. (PMID: 29227192)
2. The WOX11-LBD16 pathway promotes the acquisition of pluripotency in callus cells. (PMID: 29361138)
3. The conserved Leu or Valine residues in the coiled-coil motif are essential for the dimerization of LBD16 and LBD18 transcription factors. (PMID: 28336771)
4. LBD16 plays a key role in xylem pole pericycle cells during giant cell and gall development. (PMID: 24803293)
5. PUCHI interacts with LBD16 and LBD18 to regulate lateral root primordium development and lateral root emergence. (PMID: 23749813)
6. LBD16, LBD29, and LBD18 are involved in pericycle cell cycle progression in response to auxin. (PMID: 22699776)
7. Overexpression of LBD genes promotes callus formation independently of exogenous phytohormones, while suppression of LBD function inhibits callus induction. (PMID: 22508267)
8. The localized activity of LBD16/ASL18 and related LBD/ASLs is involved in the symmetry breaking of lateral root founder cells, a crucial step in root system architecture. (PMID: 22278921)
9. LBD16 and LBD18 may function cooperatively in lateral root formation. (PMID: 19717544)

KEGG: ath:AT2G42430

STRING: 3702.AT2G42430.1

UniGene: At.13375