lonp-1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
lonp-1 antibody; C34B2.6 antibody; Lon protease homolog antibody; mitochondrial antibody; EC 3.4.21.53 antibody
Target Names
lonp-1
Uniprot No.
Target Background
Function
LonP1 is an ATP-dependent serine protease localized to the mitochondrial matrix. Its primary function is the selective degradation of misfolded, unassembled, or oxidatively damaged polypeptides, as well as certain short-lived regulatory proteins. LonP1 may also exhibit chaperone activity in the assembly of inner mitochondrial membrane protein complexes. Furthermore, it plays a role in regulating mitochondrial gene expression and maintaining the integrity of the mitochondrial genome through site-specific binding to mitochondrial DNA. Evidence suggests LonP1 is involved in the degradation of the transcription factor, ATFS-1, within the mitochondrion.
Database Links
Protein Families
Peptidase S16 family
Subcellular Location
Mitochondrion matrix.
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