lrit2 Antibody
Description
Molecular and Genetic Context of LRIT2
The LRIT2 gene (Entrez Gene ID: 340745) encodes a protein-coding protein characterized by:
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Structural domains: Leucine-rich repeats (LRRs), immunoglobulin-like (Ig-like) domains, and a transmembrane region .
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Genomic localization: Chromosomal location and transcript variants remain areas of active research.
LRIT2 Antibody Characteristics
The recombinant LRIT2 antibody (Catalog No. ABIN2724665) is produced for research applications with the following specifications :
| Parameter | Detail |
|---|---|
| Expression System | HEK-293 Cells |
| Tag | Myc-DYKDDDDK (C-terminal) |
| Molecular Weight | 60 kDa |
| Purity | >80% (SDS-PAGE, Coomassie staining) |
| Concentration | 50 μg/mL |
| Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Storage | -80°C (≤3 freeze-thaw cycles recommended) |
Production and Validation
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Cloning: Derived from an end-sequenced ORF clone to ensure sequence accuracy .
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Quality Control: Validated via immunoblotting and Coomassie staining for purity .
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Applications:
Research Utility
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Target Localization: Facilitates studies on LRIT2’s role in cellular processes, particularly in membrane-associated signaling.
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Limitations: No peer-reviewed studies on LRIT2 knockout models or truncated isoforms are currently available, highlighting a gap in functional characterization.
Handling and Stability
Product Specs
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
