mak-2 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4.
Form
Liquid
Lead Time
14-16 weeks (made-to-order)
Synonyms
mak-2 antibody; C44C8.6MAP kinase-activated protein kinase mak-2 antibody; MAPK-activated protein kinase mak-2 antibody; EC 2.7.11.1 antibody
Target Names
mak-2
Uniprot No.
Target Background
Function
MAK-2 is a serine/threonine-protein kinase involved in maintaining synapse and axon morphology. It also contributes to touch neuron axon regeneration following injury. This function is mediated through the regulation of cebp-1 mRNA stability downstream of the dlk-1, mkk-4, and pmk-3 signaling cascade. MAK-2 may additionally play a role in body wall muscle contraction and the formation of muscle attachments (muscle arm extensions) between the body wall and motor axons in both the dorsal and ventral nerve cords.
Database Links
Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Subcellular Location
Perikaryon. Nucleus. Cell junction, synapse.
Tissue Specificity
Expressed in pharynx, intestine and body wall muscles. Expressed in the nervous system.
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