Mab21l2 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
Mab21l2Protein mab-21-like 2 antibody
Target Names
Mab21l2
Uniprot No.

Target Background

Function
Mab21l2 is essential for various aspects of embryonic development. Its roles include the normal development of the eye, notochord, neural tube, and other organ systems; it is also crucial for embryonic turning.
Gene References Into Functions
  • In mouse embryos, Mab21l2 exhibits strong expression in the developing eye, pharyngeal arches, and limb buds. (PMID: 24906020)
  • Mab21l2 plays a critical role in both heart and liver development via septum transversum mesenchyme (STM) formation. (PMID: 22412967)
  • Mab21l2 is required during embryonic development for processes such as embryonic turning, notochord formation, neural tube formation, and the development of other organ tissues. (PMID: 11857508)
  • Studies indicate that Mab21l2 has crucial roles in retina development and ventral body wall formation. (PMID: 15385160)
Database Links
Protein Families
Mab-21 family
Subcellular Location
Nucleus. Cytoplasm.
Tissue Specificity
Expressed in the adult cerebellum and eye, with lower levels in the adult forebrain. In embryos at 10.5 days post-coitum strongly expressed in the rostral and distal regions of the developing neural retina, with no expression immediately adjacent to the c

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