mbl-1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 Weeks (Made-to-Order)
Synonyms
mbl-1 antibody; K02H8.1 antibody; Muscleblind-like protein antibody; CeMBL antibody
Target Names
mbl-1
Uniprot No.
Target Background
Function
This antibody binds to RNA containing the repeat sequences 5'-CUG-3' and 5'-CCUG-3'.
Gene References Into Functions
The Muscleblind-like (MBNL) proteins, in addition to their established roles in muscle function, also play a crucial role in neuronal development and synapse formation.[1] Further research has identified six isoforms of the K02H8.1 protein. One isoform demonstrated a strong binding affinity for CUG and CCUG repeats, comparable to that of MBNLs. Interestingly, while expression driven by the K02H8.1 promoter was absent in muscle tissue, it was detected in neurons surrounding the pharynx.[2]
Database Links
Protein Families
Muscleblind family
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in neurons around the pharynx.
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