MEIS3 Antibody
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Product Specs
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid repeated freeze-thaw cycles.
Lead Time
Typically, we can ship products within 1-3 business days after receiving your order. Delivery times may vary depending on the purchase method or location. Please contact your local distributor for specific delivery information.
Synonyms
Homeobox protein meis3 antibody; Meis homeobox 3 antibody; Meis1 myeloid ecotropic viral integration site 1 homolog 3 antibody; Meis1 related protein 2 antibody; Meis1-related protein 2 antibody; meis3 antibody; MEIS3_HUMAN antibody; MRG2 antibody
Target Names
MEIS3
Uniprot No.
Target Background
Function
MEIS3 antibody is a transcriptional regulator that directly modulates PDPK1 expression, thereby promoting the survival of pancreatic beta-cells. It also regulates the expression of NDFIP1, BNIP3, and CCNG1.
Gene References Into Functions
- Research findings support a model where Meis3 is crucial for neural crest proliferation, migration into, and colonization of the gut. Its loss leads to significant defects in enteric nervous system development. PMID: 26354419
- This work suggests that the transcriptional activity of all members of the Meis/Prep Hth protein family is subject to autoinhibition by their Hth domains. The Meis3.2 splice variant encodes a protein that circumvents this autoinhibitory effect. PMID: 20553494
Protein Families
TALE/MEIS homeobox family
Subcellular Location
Nucleus.
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