METAP1 Antibody, FITC conjugated
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
We typically dispatch orders within 1-3 business days of receipt. Delivery times may vary depending on the shipping method and destination. Please contact your local distributor for specific delivery information.
Synonyms
AMPM1_HUMAN antibody; DKFZp781C0419 antibody; KIAA0094 antibody; MAP 1 antibody; MAP1A antibody; MetAP 1 antibody; metap1 antibody; MetAP1A antibody; Methionine aminopeptidase 1 antibody; Peptidase M 1 antibody
Target Names
METAP1
Uniprot No.
Target Background
Function
Methionine aminopeptidase 1 (MetAP1) is an enzyme that removes the N-terminal methionine from nascent proteins during translation. This process is often observed when the second amino acid in the protein sequence is small and uncharged (such as Ala, Cys, Gly, Pro, Ser, Thr, or Val). MetAP1 is essential for normal cell cycle progression.
Gene References Into Functions
- Research suggests that pyridinylpyrimidine-based molecules exhibit species-specific activity against methionine aminopeptidases (MetAPs). PMID: 23767698
- Studies have shown that human MetAP1 can fully compensate for the loss of yeast MetAP1, indicating a similar biological function between the two proteins. PMID: 12144506
- Findings indicate that MetAP1 plays a crucial role in the G(2)/M phase of the cell cycle and could be a potential target for the development of new anticancer agents. PMID: 17114291
- Human MetAP1 differs from other members of the MetAP superfamily in terms of the number of metal ions involved in catalysis and its likely mechanism. PMID: 17929833
Database Links
Protein Families
Peptidase M24A family, Methionine aminopeptidase type 1 subfamily
Subcellular Location
Cytoplasm.
Quick Inquiry
Personal Email Detected
Please use an institutional or corporate email address for inquiries. Personal email accounts ( such as Gmail, Yahoo, and Outlook) are not accepted. *
