MIOS Antibody, Biotin conjugated

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In Stock

Product Specs

Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Typically, we can ship your orders within 1-3 business days of receipt. Delivery time may vary depending on the purchase method and location. Please consult your local distributor for specific delivery estimates.
Synonyms
MIOS antibody; GATOR complex protein MIOS antibody; Missing oocyte meiosis regulator homolog antibody
Target Names
Uniprot No.

Target Background

Function
MIOS Antibody, Biotin conjugated, functions as a component of the GATOR subcomplex GATOR2. It operates within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activating mTORC1 and the TORC1 signaling pathway, MIOS Antibody inhibits the GATOR1 subcomplex. Its regulation is negatively influenced by the upstream amino acid sensors SESN2 and CASTOR1.
Database Links

HGNC: 21905

OMIM: 615359

KEGG: hsa:54468

STRING: 9606.ENSP00000339881

UniGene: Hs.520215

Protein Families
WD repeat mio family
Subcellular Location
Lysosome membrane.

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