MORC4 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
MORC4 antibody; CRH4 antibody; At5g50780 antibody; MFB16.18 antibody; Protein MICRORCHIDIA 4 antibody; AtMORC4 antibody; EC 3.6.-.- antibody; Protein CRT1-homolog 4 antibody; CRT1-h4 antibody
Target Names
MORC4
Uniprot No.

Target Background

Function
MORC4 exhibits ATPase activity and non-specific DNA/RNA binding. It possesses endonuclease activity and is likely involved in DNA repair. A component of the RNA-directed DNA methylation (RdDM) machinery, MORC4 is essential for gene silencing and may regulate chromatin architecture to maintain this silencing. In conjunction with MORC7, it suppresses numerous non-methylated protein-coding genes, particularly those involved in pathogen response. MORC4 acts as a positive regulator of defense against the oomycete *Hyaloperonospora arabidopsidis* (Hpa).
Database Links

KEGG: ath:AT5G50780

STRING: 3702.AT5G50780.1

UniGene: At.29713

Protein Families
MORC ATPase protein family
Subcellular Location
Nucleus.

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