MSI5 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
MSI5 antibody; At4g29730 antibody; T16L4.240 antibody; WD-40 repeat-containing protein MSI5 antibody
Target Names
MSI5
Uniprot No.

Target Background

Function
MSI5 is a core histone-binding subunit. It may target chromatin assembly factors, chromatin remodeling factors, and histone deacetylases to their histone substrates. This targeting is regulated by nucleosomal DNA. MSI5 works in conjunction with PDP1 and MSI4/FVE to modulate the PRC2 complex's function on FLC.
Gene References Into Functions
Arabidopsis MSI4 (also known as FVE) and MSI5, homologs of human Retinoblastoma-Associated Proteins 46/48 (RbAp46/48), exhibit functional redundancy in silencing various siRNA-targeted loci. (PMID: 22102827)
Database Links

KEGG: ath:AT4G29730

STRING: 3702.AT4G29730.1

UniGene: At.31893

Protein Families
WD repeat RBAP46/RBAP48/MSI1 family
Subcellular Location
Nucleus.

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