MSL10 Antibody

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Product Specs

Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
MSL10; At5g12080; F14F18.230; MXC9.3; Mechanosensitive ion channel protein 10; Mechanosensitive channel of small conductance-like 10; MscS-Like protein 10; AtMSL10
Target Names
MSL10
Uniprot No.

Target Background

Function
MSL10 is a mechanosensitive channel that opens in response to stretch forces within the membrane lipid bilayer.
Gene References Into Functions
  1. Research indicates that MSL10 plays a role in the wound-triggered early signal transduction pathway and potentially in regulating the positive feedback synthesis of JA. PMID: 26356550
  2. The plant-specific N-terminal domain of MSL10 possesses the capability to induce cell death. This activity is regulated by phosphorylation, and MSL10 exhibits two distinct functions: one as an ion channel and another as an inducer of cell death. PMID: 25052715
  3. MSL10 demonstrates asymmetrical activation/inactivation kinetics, with the channel closing at significantly lower tensions compared to its opening. PMID: 23112188
  4. MSL9 and MSL10 are essential for mechanosensitive channel activities observed in protoplasts derived from root cells. PMID: 18485707
Database Links

KEGG: ath:AT5G12080

STRING: 3702.AT5G12080.1

UniGene: At.28024

Protein Families
MscS (TC 1.A.23) family
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Tissue Specificity
Detected in the root tip and throughout the vasculature of the root and leaf.

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