MTN1 Antibody
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Product Specs
Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
MTN1 antibody; MTAN antibody; MTAN1 antibody; At4g38800 antibody; T9A14.80 antibody; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 antibody; AtMTN1 antibody; EC 3.2.2.9 antibody; 5'-methylthioadenosine nucleosidase antibody; MTA nucleosidase antibody; MTA/SAH nucleosidase 1 antibody; AtMTAN1 antibody; S-adenosylhomocysteine nucleosidase antibody; AdoHcy nucleosidase antibody; SAH nucleosidase antibody; SRH nucleosidase antibody
Target Names
MTN1
Uniprot No.
Target Background
Function
This antibody targets 5'-methylthioadenosine nucleosidase (MTN1), an enzyme crucial in the methionine cycle. MTN1 catalyzes the irreversible cleavage of 5'-methylthioadenosine (MTA) into adenine and 5'-methylthioribose. This activity contributes to the maintenance of S-adenosylmethionine (AdoMet) homeostasis and is essential for sustaining high rates of ethylene biosynthesis. Importantly, MTN1 exhibits no activity towards S-adenosylhomocysteine (SAH/AdoHcy).
Gene References Into Functions
- MTA's role as a critical metabolite linking the Yang cycle and polyamine biosynthesis, highlighting MTN1's importance within the Yang cycle. (PMID: 20345605) [Link]
- High-resolution structural determination of 5'-methylthioadenosine nucleosidase from Arabidopsis thaliana (AtMTAN). (PMID: 16909418) [Link]
- Kinetic characterization of AtMTAN1. (PMID: 18342331) [Link]
- Specific inhibition of ATMTN1 methylthioadenosine nucleosidase activity by Ca(2+)-bound CBL3. (PMID: 18945934) [Link]
Database Links
Protein Families
PNP/UDP phosphorylase family, MtnN subfamily
Tissue Specificity
Expressed in roots, leaves, stems, cauline leaves and flowers.
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