myo52 Antibody

1. Rng8 and Rng9 accumulate on the fusion focus, a process dependent on Myo51 and tropomyosin Cdc8. A tropomyosin mutant allele, while not affecting actin binding, compromises Rng8/9 localization, resulting in multiple stable dots instead of a single focus. In contrast, myo51 deletion does not significantly affect fusion focus coalescence. (PMID: 28410370)
2. Myo52p, devoid of cargo or present as single molecules with small cargoes, exhibits processive movement along actin-Cdc8p cables in vivo. (PMID: 24196839)
3. The motor activity of Myo52 may exert tension on cables, facilitating their extension and efficient assembly. This is supported by the observation that artificially tethering actin cables to the nuclear envelope via a Myo52 motor domain influences cable assembly. (PMID: 23051734)
4. Myo52 promotes microtubule catastrophe by enhancing Tip1 removal from the plus end of growing microtubules at the cell tips. (PMID: 19808886)
5. Myo52, a form of myosin type V, transports Bgs1 to the cell equator, ensuring the precise deposition of beta-1,3-glucan at the leading edge of the primary septum. (PMID: 16421926)
6. The in vivo movement of the type V myosin Myo52 necessitates dimerization but is independent of the neck domain. (PMID: 18003699)

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KEGG: spo:SPCC1919.10c

STRING: 4896.SPCC1919.10c.1