NKX6-3 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Lead Time
Typically, we can ship the products within 1-3 business days after receiving your orders. Delivery time may vary depending on the purchase method or location. For specific delivery times, please contact your local distributors.
Synonyms
FLJ25169 antibody; Homeobox protein Nkx 6.3 antibody; Homeobox protein Nkx-6.3 antibody; NK6 homeobox 3 antibody; NKX6-3 antibody; NKX6.3 antibody; NKX63 antibody; NKX63_HUMAN antibody
Target Names
NKX6-3
Uniprot No.
Target Background
Function
NKX6.3 is a putative transcription factor potentially involved in the patterning of the central nervous system and pancreas.
Gene References Into Functions
- Research suggests that NKX6.3 inhibits ROS production by inducing the expression of Hace1 through down-regulation of NF-kB and DNMT1 activity in gastric epithelial cells. PMID: 28584243
- The expression level of NKX6.3 is associated with the regulation of gastric cancer progression and the expression of Wnt/beta-catenin and Rho-GTPase pathway-related genes in clinical samples. PMID: 27333045
- Findings suggest that NKX6.3 might serve as a master regulator of gastric differentiation by influencing SOX2 and CDX2 expression, and its inactivation may lead to intestinal metaplasia in gastric epithelial cells. PMID: 26743476
- Data indicates that NK6 homeobox 3 (NKX6.3) may control the fate of gastric mucosal cells and function as a gastric tumor suppressor. PMID: 26314965
Database Links
Subcellular Location
Nucleus.
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