This antibody targets a protein that may function as a substrate-specific adapter for the E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB). This complex mediates the ubiquitination and subsequent degradation of target proteins via the proteasome. The protein may play a crucial role in auxin-mediated organogenesis and root gravitropic responses.
Expressed in the cotyledon cells that would differentiate into vascular bundles. Also detected in the apical meristem and young flowers. Highly expressed in primary root tips.
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