NSN1 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% ProClin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (Made-to-order)
Synonyms
NSN1 antibody; DGP4 antibody; At3g07050 antibody; F17A9.21 antibody; Guanine nucleotide-binding protein-like NSN1 antibody; Nucleolar GTP-binding protein NSN1 antibody; DAR GTPase 4 antibody; Protein nucleostemin-like 1 antibody
Target Names
NSN1
Uniprot No.
Target Background
Function
NSN1 antibody targets a protein involved in several crucial plant developmental processes. It regulates the expression of genes impacting epidermal cell differentiation (e.g., *CLV3*, *STM*, *KNAT1*, *CUC2*, *AG*, *YAB5*, *FIL*, *AS2*, *PHB*, and *PHV*), influencing both meristem activity and leaf polarity. Furthermore, NSN1 plays a role in cellular proliferation and flower development, likely by counteracting apical dominance through *AG* downregulation. Its importance extends to embryogenesis, leaf and cotyledon development, and leaf polarity establishment. Critically, NSN1 modulates ribosome biogenesis within the nucleolus, impacting plant growth and senescence. In vitro studies demonstrate its GTPase and RNA-binding activities, and its association with ribosomes.
Gene References Into Functions
Supporting evidence highlights NSN1's functional roles:
1. Within a complex regulatory network, NSN1 represses *AG* expression and works additively with AP2 in floral organ specification (PMID: 22357616).
2. NSN1 (AT3G07050) is identified as a novel GTPase essential for embryogenesis, leaf development, and leaf polarity (PMID: 22058024).
Database Links
Protein Families
TRAFAC class YlqF/YawG GTPase family
Subcellular Location
Nucleus. Nucleus, nucleolus.
Tissue Specificity
Mostly expressed in flowers, siliques and inflorescence apex, and, to a lower extent, in stems and leaves.
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