Oncomodulin exhibits calmodulin-like activity, influencing enzyme activation and growth regulation. It binds two calcium ions.
Gene References Into Functions
Oncomodulin expression commences between postnatal day 2 and P4, reaching peak levels as early as P10. Notably, it is exclusively expressed by outer hair cells (OHCs) in the rat cochlea, appearing after efferent innervation along the cochlear spiral between P2 and P4. PMID: 14978725
Oncomodulin stands out as a novel growth factor for neurons in the mature central and peripheral nervous systems. PMID: 16699509
The solution structure of Ca2+-free oncomodulin has been reported. PMID: 17766386
Leucine 85 serves as a crucial determinant of divalent ion affinity in rat beta-parvalbumin. PMID: 19075559
Oncomodulin serves as a growth factor for neurons in the mature central and peripheral nervous systems. PMID: 16699509