OCM Human
Description
Potential Misinterpretation of Acronyms
The acronym "OCM" appears in multiple contexts across scientific disciplines, but none align with a compound named "OCM Human":
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Outline of Cultural Materials (OCM): A classification system for ethnographic research ([Source 6] ).
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Organic Carbon Matter: A general term in environmental science, unrelated to human-specific compounds.
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Oxidative Coupling of Methane: A chemical process in industrial catalysis, irrelevant to human biology.
No peer-reviewed publications, clinical trials, or regulatory documents reference "OCM Human" as a discrete compound.
Analysis of Human-Related Compounds
While "OCM Human" remains unidentified, human biology involves critical organic and inorganic compounds. Key findings from reviewed sources include:
Table 1: Essential Organic Compounds in Humans
Table 2: Trace Elements in Humans
| Element | Symbol | % Body Mass | Role | Sources |
|---|---|---|---|---|
| Iron | Fe | 0.006% | Oxygen transport (hemoglobin) | |
| Zinc | Zn | 0.0032% | Enzyme cofactor | |
| Copper | Cu | 0.0001% | Electron transport |
Relevant Research Methodologies
If "OCM Human" refers to an uncharacterized compound, methodologies for its identification might include:
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Radiolabelled Studies: Tracking absorption, metabolism, and excretion (AME) using isotopes like ¹⁴C ([Source 7] ).
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Metabolite Profiling: High-resolution mass spectrometry (HRMS) to identify unknown compounds ([Source 12] ).
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Genomic Databases: Cross-referencing with human pangenome data to detect novel biomolecules ([Source 8] ).
Recommendations for Further Inquiry
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Verify Terminology: Confirm whether "OCM Human" is a proprietary term, typographical error, or emerging research concept.
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Explore Databases:
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Consult Interdisciplinary Sources: Cross-reference anthropology (OCM taxonomy) and biochemistry for potential overlaps.
Product Specs
MKHHHHHHAS ITDVLSADDI S ITDVLSADDI AAALQECRDP DTFEPQKFFQ TSGLSKMSAN QVKDVFRFID NDQSGYLDEE ELKFFLQKFE SGARELTESE TKSLMAAADN DGDGKIGAEE FQEMVHS.
Product Science Overview
The recombinant human Oncomodulin-1 is produced in E. coli and has a molecular mass of approximately 13.21 kDa. It consists of 117 amino acid residues and is fused to a 9 amino acid His tag at the N-terminus . Oncomodulin-1 contains two EF-hand domains, which are helix-loop-helix structural domains capable of binding calcium ions with high affinity .
Oncomodulin-1 serves several important biological functions:
- Calcium Binding: As a high-affinity calcium ion-binding protein, Oncomodulin-1 plays a crucial role in calcium signaling pathways.
- Growth Regulation: It exhibits calmodulin-like activity, which is involved in enzyme activation and growth regulation .
- Axon Regeneration: Oncomodulin-1 acts as a macrophage-derived growth factor that promotes axon regeneration in retinal ganglion cells (RGCs). It is secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration .
Recombinant human Oncomodulin-1 is used in various research applications, including:
- Western Blotting: It is commonly used as a protein marker in Western blotting experiments.
- Cancer Research: Due to its presence in tumors, Oncomodulin-1 is studied for its potential role in cancer development and progression .
- Neuroscience Research: Its ability to promote axon regeneration makes it a valuable tool in neuroscience research, particularly in studies related to optic nerve injuries .
