OMT1 Antibody
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Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
OMT1 antibody; COMT1 antibody; At5g54160 antibody; K18G13.3 antibody; Flavone 3'-O-methyltransferase 1 antibody; AtOMT1 antibody; EC 2.1.1.42 antibody; Acetylserotonin O-methyltransferase OMT1 antibody; EC 2.1.1.4 antibody; Caffeate O-methyltransferase 1 antibody; EC 2.1.1.68 antibody; Quercetin 3'-O-methyltransferase 1 antibody
Target Names
OMT1
Uniprot No.
Target Background
Function
OMT1 Antibody targets an enzyme that methylates hydroxyl (OH) groups on flavonoid compounds. It converts quercetin into isorhamnetin, but dihydroquercetin is not a substrate. Additionally, it catalyzes the methylation of monolignols, which are lignin precursors. While it does not contribute to the phenylpropanoid pattern of pollen tryphine, OMT1 is likely involved in isorhamnetin glycoside biosynthesis. Notably, it plays a role in melatonin biosynthesis, functioning as acetylserotonin O-methyltransferase. This enzyme catalyzes the transfer of a methyl group onto N-acetylserotonin, resulting in the production of melatonin (N-acetyl-5-methoxytryptamine).
Gene References Into Functions
- Lignin degradative analysis revealed the release of a 5-hydroxyconiferyl alcohol (5OHG)-5OHG-G trimer from the Atomt1 mutant. PMID: 20652169
- Research has determined the 3-D structure of Arabidopsis thaliana O-methyltransferase, AtOMT1, as well as its dynamic behavior when complexed with its substrate. PMID: 15331056
Database Links
Protein Families
Class I-like SAM-binding methyltransferase superfamily, Cation-independent O-methyltransferase family, COMT subfamily
Tissue Specificity
Expressed in seedlings, leaves, stems, flowers and siliques, mostly in vascular tissues. Mostly expressed in the apical part of the stems and in roots. Expressed in the endothecium and the epidermal anther, but not in the tapetum. Also detected in all epi
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