At1g14010 Antibody

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Description

Identification of the Compound

  • None of the provided sources mention this gene or an associated antibody.

  • The search results focus on angiotensin II type 1 receptor (AT1R) antibodies, which are unrelated to the Arabidopsis gene identifier.

Analysis of Search Results

The provided materials discuss antibodies targeting human and mammalian proteins, such as:

  • AT1R antibodies for cardiovascular research .

  • Monoclonal antibodies for cancer, diagnostics, and organ transplantation .

  • Recombinant antibody engineering techniques .

No studies, commercial products, or validation data related to "At1g14010" (a plant gene) or its hypothetical antibody were identified.

Potential Reasons for Missing Data

  • Nomenclature Error: "At1g14010" may be a typographical error (e.g., confusion with "AT1R," a well-characterized human receptor).

  • Specificity: Antibodies targeting plant genes are less commonly studied in clinical or pharmacological contexts compared to human/mammalian targets.

  • Commercial Availability: No vendors or research tools for "At1g14010 Antibody" are listed in the sources.

Recommendations for Further Investigation

To address this gap:

  1. Verify the correct gene/protein identifier (e.g., AT1R vs. At1g14010).

  2. Consult plant-specific databases (e.g., TAIR, UniProt) for Arabidopsis gene annotations.

  3. Explore antibody-generation platforms (e.g., ABCD database, recombinant engineering ) for custom antibody development.

Key Data Table: Antibody Types in Literature vs. Query

Antibody TypeTargetApplicationsSources
AT1R antibodiesHuman angiotensin receptorHypertension, organ transplant rejection
Monoclonal antibodiesCancer cells, pathogensDiagnostics, immunotherapy
Recombinant antibodiesEngineered epitopesCell biology, signal tracing
At1g14010 AntibodyNot identifiedNo dataN/A

Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
At1g14010 antibody; F16A14.23 antibody; F7A19.10 antibody; Transmembrane emp24 domain-containing protein p24delta7 antibody; p24 family protein delta2a antibody; p24delta2a antibody; p24 family protein delta7 antibody; p24delta7 antibody
Target Names
At1g14010
Uniprot No.

Target Background

Function
This antibody targets a protein involved in vesicular protein trafficking. Primarily, it functions in the early secretory pathway. It is believed to act as a cargo receptor on the lumenal side for the incorporation of secretory cargo molecules into transport vesicles. It is also thought to play a role in vesicle coat formation on the cytoplasmic side.
Database Links

KEGG: ath:AT1G14010

STRING: 3702.AT1G14010.1

UniGene: At.11347

Protein Families
EMP24/GP25L family
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein.

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