PI4KB2 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PI4KB2 antibody; PI4KBETA2 antibody; At5g09350 antibody; T5E8.150 antibody; Phosphatidylinositol 4-kinase beta 2 antibody; PI4-kinase beta 2 antibody; PtdIns-4-kinase beta 2 antibody; EC 2.7.1.67 antibody; Phosphatidylinositol 4-OH kinase beta2 antibody; AtPI4Kbeta2 antibody; PI-4Kbeta2 antibody
Target Names
PI4KB2
Uniprot No.
Target Background
Function
PI4KB2 antibody acts on phosphatidylinositol (PtdIns), catalyzing the first committed step in the production of the second messenger inositol-1,4,5-trisphosphate. This enzyme is crucial for the proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. In collaboration with PI4KB1, PI4KB2 is essential during the polarized expansion of root hairs and the elongation of pollen tubes. Functionally, it exhibits redundancy with PI4KB1 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway.
Gene References Into Functions
- The stunted rosette phenotype observed in pi4kIIIbeta1beta2 double mutants is attributed to elevated salicylic acid levels, while the reduced root length is independent of this factor. PMID: 25482755
- Genetic analysis reveals that PI4KIIIbeta1 and PI4KIIIbeta2 operate upstream of EDS1 and require functional salicylic acid biosynthesis and perception through NPR1 to manifest the dwarf phenotype. [PI4KIIIbeta2] PMID: 24758581
- Both AtPI4KIIIbeta1 and AtPI4KIIIbeta2 can function upstream of the PI-PLC. PMID: 22318862
Database Links
Protein Families
PI3/PI4-kinase family, Type III PI4K subfamily
Subcellular Location
Cell membrane. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
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