PI4KG4 Antibody

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Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PI4KG4 antibody; PI4KGAMMA4 antibody; UBDKGAMMA4 antibody; At2g46500 antibody; F11C10.19 antibody; F13A10.3 antibody; Phosphatidylinositol 4-kinase gamma 4 antibody; AtPI4Kgamma4 antibody; PI-4Kgamma4 antibody; PI4K gamma 4 antibody; EC 2.7.1.67 antibody; Ubiquitin-like domain kinase gamma 4 antibody; UbDK gamma 4 antibody
Target Names
PI4KG4
Uniprot No.

Target Background

Function
The phosphorylation of phosphatidylinositol (PI) to PI4P constitutes the initial committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate (PIP2). PIP2 serves as a precursor for the second messenger inositol 1,4,5-trisphosphate (InsP3). This kinase exhibits autophosphorylation activity and phosphorylates serine/threonine residues within protein substrates. In vitro, it has been demonstrated to phosphorylate RPN10 and UFD1.
Gene References Into Functions
  1. PI4K and PI3K are indispensable for distinct stages in the secretory and/or endocytic trafficking of CESA3. PMID: 25516570
Database Links

KEGG: ath:AT2G46500

STRING: 3702.AT2G46500.1

UniGene: At.27467

Protein Families
PI3/PI4-kinase family, Type II PI4K subfamily
Subcellular Location
Membrane; Peripheral membrane protein; Cytoplasmic side.

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