PABN1 Antibody
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Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PABN1 antibody; At5g51120 antibody; MWD22.6Polyadenylate-binding protein 1 antibody; AtPabN1 antibody; Poly(A)-binding protein 1 antibody; Nuclear poly(A)-binding protein 1 antibody; Poly(A)-binding protein I antibody; PABI antibody
Target Names
PABN1
Uniprot No.
Target Background
Function
PABN1 plays a crucial role in the formation of mRNA precursors (pre-mRNA) by catalyzing the addition of a poly(A) tail, typically composed of 200-250 nucleotides, to the upstream cleavage product. It acts as a stimulator of poly(A) polymerase (PAPOLA), enhancing the processivity of the poly(A) tail elongation reaction and regulating the length of the tail. PABN1 increases the affinity of poly(A) polymerase for RNA. Furthermore, it exhibits a high affinity for both poly(A) and poly(G) sequences. This binding activity may contribute to the protection of the poly(A) tail from degradation.
Database Links
KEGG: ath:AT5G51120
UniGene: At.24603
Subcellular Location
Nucleus speckle. Cytoplasm.
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