Os09g0533100 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
Os09g0533100 antibody; LOC_Os09g36270 antibody; OJ1112_E07.4 antibody; P0515E01.23 antibody; Pantothenate kinase 2 antibody; Pantothenic acid kinase 2) [Includes: Pantothenate kinase antibody; EC 2.7.1.33); 4'-phosphopantetheine phosphatase antibody; EC 3.1.3.-)] antibody
Target Names
Os09g0533100
Uniprot No.
Target Background
Function
This antibody targets Os09g0533100, an enzyme that catalyzes the phosphorylation of pantothenate, the initial step in CoA biosynthesis. This enzyme may play a crucial role in regulating the intracellular CoA concentration. It exhibits functional redundancy with PANK1. Notably, the phosphatase activity displays a preference for normal or oxidatively damaged intermediates of 4'-phosphopantetheine, providing strong indirect evidence that this activity pre-empts damage within the CoA pathway. Hydrolyzing excess 4'-phosphopantetheine could function as a directed overflow mechanism, preventing its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would hinder their conversion to inactive forms of CoA and acyl carrier protein.
Database Links
Protein Families
Type II pantothenate kinase family
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