PAPS2 Antibody

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Product Specs

Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PAPS2 antibody; At2g25850 antibody; F17H15.12 antibody; Nuclear poly(A) polymerase 2 antibody; PAP(II) antibody; Poly(A) polymerase II antibody; EC 2.7.7.19 antibody; Polynucleotide adenylyltransferase 2 antibody
Target Names
PAPS2
Uniprot No.

Target Background

Function
This antibody targets PAPS2, an essential protein that functions as a polymerase responsible for creating the 3'-poly(A) tail of mRNA molecules. PAPS2 is also involved in the endoribonucleolytic cleavage reaction at specific polyadenylation sites. Its specificity can be modulated through interactions with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus. Furthermore, PAPS2 mediates the polyadenylation of RNAs associated with polynucleotide phosphorylase (e.g., PNP1).
Database Links

KEGG: ath:AT2G25850

STRING: 3702.AT2G25850.2

UniGene: At.14867

Protein Families
Poly(A) polymerase family
Subcellular Location
Nucleus. Cytoplasm.
Tissue Specificity
Mostly expressed in flowers (highly in the style, receptacle and pedicel, but weakly in the vasculature of sepals) and hypocotyls, and, to a lower extent, in roots and stems. Barely detected in leaves (petioles and vascular system).

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