C27F2.10 Antibody
Description
Gene Ontology and Functional Associations
The C27F2.10 gene is linked to nematode larval development through gene ontology (GO) term enrichment analyses. Key associations include:
| GO Term | Description | Associated Genes |
|---|---|---|
| GO:0002119 | Nematode larval development | PYP-1, MRPL-16, SCO-1, C27F2.10, CYC-2.2 |
| GO:0005737 | Cytoplasmic localization | PYP-1, LSM-4, MVK-1, UNC-70, C27F2.10 |
These annotations suggest involvement in conserved developmental pathways, potentially interacting with genes like PYP-1 (protease) and CYC-2.2 (cyclin) .
Orthology and Cross-Species Relevance
C27F2.10 shares orthology with human genes implicated in cellular regulation:
| C. elegans Gene | Human Ortholog | Human Protein Function |
|---|---|---|
| C27F2.10 | BTBD10, KCTD20 | BTB domain-containing proteins involved in ubiquitination and transcriptional regulation |
This orthology implies that studies using the C27F2.10 antibody in C. elegans could provide insights into conserved molecular mechanisms relevant to human biology.
Research Applications
While no direct publications on the C27F2.10 antibody exist, its inferred uses include:
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Developmental Studies: Tracking protein expression during larval stages via immunofluorescence or Western blot .
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Genetic Interaction Mapping: Identifying partners in larval development pathways through co-immunoprecipitation.
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Comparative Genomics: Exploring functional parallels between C27F2.10 and human orthologs like BTBD10 .
Limitations and Future Directions
Current knowledge gaps include:
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Lack of structural or functional data on the C27F2.10 protein.
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Absence of validation studies (e.g., knockout phenotypes) for the antibody.
Future research should prioritize antibody validation in C. elegans models and explore its utility in studying conserved developmental pathways.
Product Specs
Composition: 50% Glycerol, 0.01M PBS, pH 7.4
