PDIL2-1 antibody targets a protein disulfide isomerase potentially crucial for pollen development, ovule fertilization, and embryo development.
In vitro studies using a GSSG/GSH-mediated oxidative protein folding system have demonstrated the oxidoreductase activity of AtPDI11 (a homologue of PDIL2-1). The a' domain active site was shown to be essential for this oxidative folding activity. PMID: 29162449