PDR2 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PDR2 antibody; MIA antibody; At5g23630 antibody; MQM1.11Probable manganese-transporting ATPase PDR2 antibody; EC 7.2.2.- antibody; Protein MALE GAMETOGENESIS IMPAIRED ANTHERS antibody; Protein PHOSPHATE DEFICIENCY RESPONSE 2 antibody
Target Names
PDR2
Uniprot No.
Target Background
Function
PDR2 antibody targets a protein that plays a critical role in manganese transport into the endoplasmic reticulum. This transport process is essential for maintaining cellular manganese homeostasis. PDR2 is also involved in pollen and root development, influencing protein secretion and transport processes. It functions alongside LPR1 and LPR2 in a pathway that regulates root meristem activity in response to phosphate availability. Under phosphate-limited conditions, PDR2 restricts SHR movement within the root meristem. This is crucial for maintaining SCR expression in the root meristem stem-cell niche and for supporting proximal meristem activity. Additionally, PDR2 can complement the yeast spf1 mutant.
Gene References Into Functions
- The LPR1-PDR2 module facilitates, under phosphate-limited conditions, cell-specific apoplastic iron and callose deposition in the meristem and elongation zone of primary roots. PMID: 25898169
Database Links
Protein Families
Cation transport ATPase (P-type) (TC 3.A.3) family, Type V subfamily
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Found in secretory vesicles of the tapetum and developing pollen grains.
Tissue Specificity
Highly expressed in root meristem. Expressed in pavement cells of trichomes, stipules, stamens and pollen grains.
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