PGBD3 Antibody

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Product Specs

Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. Store at -20°C. Avoid repeated freeze-thaw cycles.
Lead Time
We typically dispatch products within 1-3 business days after receiving your order. Delivery times may vary depending on the purchase method and location. Please consult your local distributors for specific delivery timelines.
Synonyms
PGBD3 antibody; PiggyBac transposable element-derived protein 3 antibody
Target Names
PGBD3
Uniprot No.

Target Background

Function
This antibody binds in vitro to PGBD3-related transposable elements known as MER85s. These non-autonomous 140 bp elements are characterized by the presence of PGBD3 terminal inverted repeats and the absence of internal transposase ORFs.
Gene References Into Functions
  1. The CSB-PGBD3 fusion protein is important in both health and disease, and may play a role in Cockayne syndrome. PMID: 22483866
  2. Clinical trial investigating gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  3. A domesticated PiggyBac-like transposon, PGBD3, located within intron 5 of the CSB gene, functions as an alternative 3' terminal exon. PMID: 18369450
  4. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
Database Links

HGNC: 19400

OMIM: 609413

KEGG: hsa:267004

STRING: 9606.ENSP00000387966

UniGene: Hs.49063

Subcellular Location
Nucleus.
Tissue Specificity
Expressed in heart and oocytes, but not in granulosa cells (at protein level).

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