pgp-3 Antibody
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In Stock 
Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
pgp-3 antibody; ZK455.7Multidrug resistance protein pgp-3 antibody; EC 7.6.2.2 antibody; P-glycoprotein C antibody; P-glycoprotein-related protein 3 antibody
Target Names
pgp-3
Uniprot No.
Target Background
Function
This antibody targets PGP-3, a protein that mediates ATP-dependent export of organic anions and xenobiotics from the cytoplasm. It hydrolyzes ATP with low efficiency.
Gene References Into Functions
- The DeltaF508 mutation leads to post-transcriptional destabilization and degradation of PGP-3 in C. elegans epithelial cells. PMID: 22569626
Database Links
Protein Families
ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Tissue Specificity
Intestinal cells.
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