Phospho-NACA (S43) Antibody
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In Stock 
Product Specs
Buffer
The antibody is supplied as a liquid solution in phosphate-buffered saline (PBS) containing 50% glycerol, 0.5% bovine serum albumin (BSA), and 0.02% sodium azide.
Form
Liquid
Lead Time
Typically, we can ship your order within 1-3 business days of receiving it. Delivery times may vary depending on the shipping method and destination. Please contact your local distributor for specific delivery timeframes.
Synonyms
Alpha NAC antibody; Alpha-NAC antibody; Hom s 2.02 antibody; HSD48 antibody; MGC117224 antibody; NAC-alpha antibody; naca antibody; NACA/1.9.2 antibody; NACA_HUMAN antibody; NACA1 antibody; Nascent polypeptide associated complex alpha polypeptide antibody; Nascent polypeptide associated complex alpha subunit antibody; Nascent polypeptide associated complex subunit alpha antibody; Nascent polypeptide-associated complex subunit alpha antibody
Target Names
NACA
Uniprot No.
Target Background
Function
This antibody inhibits the inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). It achieves this by binding to nascent polypeptide chains as they emerge from the ribosome, preventing their interaction with the signal recognition particle (SRP). The SRP normally targets nascent secretory peptides to the ER. Additionally, this antibody reduces the inherent affinity of ribosomes for protein translocation sites (M sites) in the ER membrane. It may also act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
Protein Families
NAC-alpha family
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Ubiquitously expressed.
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